Methadone And Morphine Together

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MY HUSBAND HAS BLADDER CANCER AND WAS PRESCRIBED 20 MG OF METHADONE EVERY MORNING. HE WAS ALSO GIVEN MORPHIN SULFATE 60 MGS TWICE A DAY. HOW SHOULD THESE MEDICINES BE TAKEN?

164 Replies (9 Pages)

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1

Debra, i dont know why his dr. prescribed both Methadone and Morphine. The Methadone is known to block or cancel out the effects of the Morphine.

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2

i take 30mg 6 times aday plus 135mg of methadone a day for stomach cancer pain is it safe what are the dangers

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3

First of all methadone is not a blocker. People mistake it for suboxone because they are both used in opiate withdraw treatment. They first made methadone in world war II...when China cut Germany off from poppy trade. Hitler had his science goons make somthing to substitute opiate pain killers and Bam methadone is born. First used as a pain killer for many years...then someone found out about its overwhelming affect on the brain. They found when a subject would take between 90mg and 200mg their opiate receptors in there brain would clog up with the methadone thus not allowing AS MANY OPIATE in. But only in a high dose. The reason they still use it fore pain is because it stays attached to your brain receptors for around three days thus making it a great long term pain reliever. When taken in a small dose it will actually compliment the morphine and help it attach to the receptors and stay there longer.

Boo ya

I have to be serious at work but here its time to play.

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4

Methadone dont cancel anything out. Some claim this because methadone is so much more powerful that lesser drugs cant be felt while one uses methadone.Looks like you would have to ask yourself why a doc would give breakthrough meds if methadone was going to cancel it out.Methadone is also stronger than morphine and yes the post put up is out of line because these drugs are not prescribed together in the fashion that was posted.However yes instant release morphine can be used as breakthrough with methadone.

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5

well greg is the closest to what he said but when your on methadone long enough and try to take lortab or percacets etc. it pretty much is worthless if you are trying to feel a high. it will still help for pain however. iv use of the morphine while on methadone will override and you will feel it but if you just take the morphine orally while taking methadone it is pretty much a waste

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6

Is it dangerous taking 25 mil morphine orally and 48 methadone drink.

I also take 5 mil valium and Percodan am 70 years old and suffer from arthritis. Presently taking Oxycontin which got me started on the OXY which I am addicted to to cover the pain but buying of the street and I hate the crap.

Please let me know about the Meth and Morp mixing...thanks all

Mike

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7

Very well put!
Would you know if it's (not wise) Possible to Cold Turky Methadone and Morphine?
What would be the hardest days first week ?
How long would it take to do so if one ever needed to?
5yrs on by doctor....
Would like trying more natural ways of helping pain(;
Thanks!
Ray

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8

If u r on 130 mgs of methone a day if u werent able to take it one day but were able to take morphine how many mgs would u have to take of the morphine to feel it?

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9

I've been taking 120 mg of methadone daily for the past 9 years for nerve pain (peripheral polyneuropathy). Methadone does not help with breakthrough pain. I've been offered oral morphine, and am seriously considering using it with the methadone. What would be a safe and effective morphine dose for a mid-60s female, average height/weight, when combined with methadone? The only high I really care about is getting rid of this damn pain! (but I'm not averse to a nice little party at the same time)

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10

Hi Guys
Im currently on Fentanyl 50 ug patch,s and Morphine solution for the breakthrough pain having just changed over from MST continus tablets 120mg a day but im suffering quite badly with withdrawls now.My doctor mentioned putting me on on Methadone for the withdrawls but then what about my pain???
would it be a possibility to take the Methadone with some sort of Opiate pain killer i,e stay on the Fentanyl or stick with the Oramorph solution or even go back on the MST continus morphine tabs? Im really at a loss with this one and my back condition is getting worse the pain is even traveling down into my thighs and buttocks. Any help and advice will be greatley apreciated.

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11

I just wanted to add that my sister accidentally passed away from a toxic mix of methadone, a muscle relaxer and morphine. I would definately check with your doctor before you mix any of these drugs. Her toxicology report was ruled an accident.

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12

WAS HOSOICE INVOLVED?

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13

Hello I just finished 5 years at a methadone clinic at 90mgs a day.Let me tell you if you can help it stay away from methadone! It is very very hard to come off of.Some say 10 times harder that heroin!Just hate to see anyone get hung up on methadone.Just remembe it's HELL to get of of!!!!!

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14

I am currently prescribed 80 MG's of Methadone per day. The dose is split 4 times throughout a 24 hour period; like so: 20 MG's pRN 6HR's.

I was not liking how the Methadone made me extremely tired and just lathargic in general. I asked my doctor if we could try a different Narcotic. He suggested trying Morphine. To make a long(ish) story short; I am happy to try the Morphine Extended Release. I had heard other people having success with the drug.

I go to fill my prescription and then go to pick it up. I realize, after reading the bottle, that the script is written for "Take 1 30 MG tablet every 12 Hours". Yeah, EVERY TWELVE HOURS. 30 MG's!!! Basic conversion and common sense would tell you that 30 MG's of Morphine MIGHT, be equal to 10 MG's of Methadone!

The point of this story is just to warn people to make it very clear to your doctor that there is a Narcotic Conversion Table. I was absolutely shocked when I had to explain over the phone to a Doctor that there was a conversion and that Methadone was FAR stronger then Morphine.

Needless to say, I now have a new doctor who didn't get his MD from a Cracker Jack Box... ;)

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15

you got it dead on

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16

Been in pain mgmnt for 15yrs. On 30mg Roxys for yrs ( percs not option as causes liver failure...and in addition I have erosive gastritis and bleeding ulcers ) ....but practice decided on jan 1 to stop prescribing roxy's. Saw a jackass who put me on methadone and morphine ( he knows i'm on klonopin and flexeril too!)And listed my; brain injury, heart condition and stomach problems. He still prescribed it! I vomited for past 2 days! Guess I can't take it! Will be seeing new doc! And this one will prescribe roxys! Roxy's have far fewer adverse side effects and overdoses occur far more often with methadone/morphine! I am so SICK ofDr's letting DEA protocols (fact that they are a pain ) dictate what is prescribed! This crap makes me woozy! I can't drive...can't work on my 2nd bachelors! I really hope new doc is as good as he sounds! And prescribes what works! I've never felt "euphoric" on roxy's! Doesn't make me woozy...it only helps with pain! I shouldn't be punished cause some people overtake meds etc etc! IF ANYONE KNOWS OF A GOOD PAIN DR IN VEGAS WHO STILL PRESCRIBES ROXYS...PLZ LET ME KNOW!!!! ONE I KNOW OF..WELL, WILL TAKE WEEKS TO GET SEEN! I WANT OFF THIS STUFF NOW..MAKING ME HIGH...MAKING ME VOMIT!

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17

Well i used to take dilaudid pills and then went on 130mg. Of methadone i chose to walk off my clinic and just go cold turkey w nothing at all day one didn't feel too bad but day two startex feeling bad then day three felt like i wanted to die...by day five i guess i took some ativans and that took the edge off even though it didn't make me feel really much better then by day eight i went back to my clinic and unsuccessfully tried to get dosed that's how bad i felt then after like day twelve i believe i started taking a few morphine pills a day then that got me thru it but then got me back started on my pill habit all over again but normally people have told me that the really bad part will last anywhere between one week to a few minths because depending on the person and thier body and old dosage and whatever else they may or may not be taking along w the other stuff those are all facwill feel and for how long it it will last
once again I'm not a doctor or anything just telling you from personal experience need anymore advice feel free to ask ok hope this helps you out at least a little bit.....really much better then by day eight i tried unsuccessfully to go to the clinic

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18

I was reading into methadone and morphine mixed. This was a fatal mistake my little brother made in 2008. Nearly five years later, I am still so hurt and I strive to find the answers. I've heard of several other deaths with these two drugs; it sucks.

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19

Yes, just got the toxicology report from my daughter today. Cause of death was Morphine and Methadone....given by the Dr. She was 44 and went to sleep...her heart stopped..it was an accident. .This stuff is Very dangerous....

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20

due to serious back condition, my best friend was put on methadone because he didn't like the "high" of oxycontin and the methadone does not alter his mind at all. however, despite never being "addicted" [maintained and never increased doses, cut out doses when he could stand the pain etc] his body did become dependent anyway. He had surgery finally and now is doing much better pain wise, so has begun to taper, achieving easily going from 10 mg 3 x a day to 2.5 one x a day now, with very little discomfort or irritation, he says he needs a week or two at each new dose to adjust to the increase in discomfort cutting the meds provokes, but once adjusted, pain gets better too. no withdrawal symptoms yet aside from that adjustment and a couple of warm flashes so far. He's nervous about putting that last bit down, after all he's read about w/d symptoms even if separating at such a low dose...but is determined to see this through, doesn't want to take it as his pain is much improved by surgery and is not willing to acquire an addiction on top of general dependance...and we'll be there for support definitely. He has gotten scripts for things to cover some of the possible symptoms, should they occur, like for nausea, anxiety, sleep, muscle spasm etc. l think that was smart, but he/we are hoping he won't need them. The point is, go slow, taper as you are able to w/out significant WD symptoms, balancing the reduction based on pain level improvements and keeping wd symptoms at bay and I bet you'll be fine. best of luck, and pray for my bro, if you pray...I'll be praying for you. peace

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164

Re: licensetospill (# 5) Expand Referenced Message

You just have to take it before you take your methadone, and it will strengthen the methadone, similar to the way 200mg of Morphine or Dolcontin work. However, this has been my experience. It's important to remember that people are different, and what works for one person may not work for another. Analysing patients can be time-consuming and challenging due to the diversity in people. Sometimes, doctors may get fed up and start prescribing medications without thorough diagnosis. If they can clearly see you are dealing with addiction, they might just refuse treatment due to limited time. The prevalence of drugs on the streets can be largely attributed to doctors and big pharmaceutical companies. It's the government's fault that things are the way they are!

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163

Re: yellowtail (# 4) Expand Referenced Message

Exactly my point as well. It's just that methadone is 100 times stronger, so how are you going to feel something that isn't even half as strong as methadone? Logic! I am from Norway, so I apologize for any spelling mistakes. "Jeg prater norsk" or "jeg snakker norsk" is more correct to say in Norwegian. However, we have a lot of Americans here who speak English. Doctors, and the whole American pharmaceutical industry, or 'Big Pharma,' are just after money. They may sometimes manipulate doctors without them even knowing it. But that's really what it comes down to at the end of the day, and everything in between. Good, glad you get it!

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162

Re: Greg (# 3) Expand Referenced Message

I've been familiar with methadone for about 15 years now. Yes, I was an addict, but I can tell you from experience that methadone is 100 times more potent than most other medications in the same group. Methadone is one of the most potent, so whether the dose is high or not, other substances might feel weak or nearly ineffective in comparison. They are doing their job, but methadone is simply stronger, hence you might not feel their effects. Methadone doesn't block anything. Trust me, I've experimented with it. Don't always believe what doctors say because in the United States, opioids are classed as Schedule II drugs, but here in Norway, and in the rest of the EU, they're rated schedule one because of their high addictive potential. There's an impression among some doctors who seem more interested in making money. Fortunately for me, I don't pay anything for my medications which are at the moment methadone, Lyrica, and Stesolid (Norwegian Diazepam). I've been on these medicines for 15 years and have started to notice their side effects more prominently after 10 years. Methadone will adversely impact your lifespan; it can cut around ten years from your life because it harms you from the inside. I wish I could get off methadone, but it's incredibly painful to do so, and it doesn't help that these medications are provided for free. I've seen how methadone withdrawal can lead to severe health issues, such as causing people's hearts to stop due to their long-term dependency on it. Basically, methadone might help you cope, but it slowly causes harm. Synthetic opioids are the most harmful in this regard. Dolcontin, for example, is a long-acting opioid (12 hour release) and shouldn't be confused with Oxycontin as it almost has the same dramatic effect like H, due to the rapid turbo effect on pain - I know this from personal experience.

In contrast, long-lasting morphine seems safer and is sourced from natural substances, not synthetic. Always ask your doctor for advice on these drugs. They can seriously mess up your psychological health, alter your brain structure, and you typically need more and more. It is concerning that methadone is still prescribed to cancer patients because it hastens their decline. In Norway, we are required to have heart health check-ups every three months due to potential damage from methadone. In my view, methadone should never have been used. However, don't just take my word for it. Check with people from Norway, Denmark, and Sweden. We've even started using Sevredol (24-hour morphine drug) in Norway, but it might be a half-synthetic opioid; I'm not entirely sure. I strongly advise you to avoid methadone because it harms anyone who takes it. Especially cancer patients, it's similar to Fentanyl, just slightly less potent. Do your research and I assure you that you'll find exactly what I've been talking about here. Perhaps check out sites from England and surrounding countries. It's disheartening to see how America treats its own people. Having to pay for essential medications is unfathomable for me. After all, these are drugs that you need to survive and if you can't afford them, what then? It's a multi-million dollar industry. Why can't America offer free healthcare to everyone? Sure, some services should be paid for, but not when it comes to life-saving medications, especially if you're on a program that provides them for free. I've written quite a bit here, but I hope it helps you in some way. Perhaps you're already aware, but it's important to consider the pros and cons before taking any medication.

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161

Re: martin (# 10) Expand Referenced Message

You need to get off the fentanyl! ASAP. Even under a drs care!

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160

Methadone prevents other pain medications from working properly. That doctor is crazy.

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159

Re: cynthia (# 8) Expand Referenced Message

What do you mean by "feel it?" If you've been prescribed morphine with methadone then that is for pain. Your concern is better spent at understanding the equivelncy of morphine per mg is to methadone is per mg in the abilities of both to prevent pain. If you want to know how much to take to feel it, then you are using for reacreation and not how it is prescribed.

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158

Adubb (# 22) what language r u speaking because u make no sense

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157

Re: Bobutz (# 144) Expand Referenced Message

If not longer, then you won't be the same person you were before you got on methadone.

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156

Re: John (# 1) Expand Referenced Message

Wrong... methadone doesn't block morphine...that's subutex or naltrexone..the body when ingesting methadone converts it to diamorphine... Basically, that's what he's been prescribed...I do think it's a bit weird tho, when methadone is usually a replacement for opiate addiction... But then again methadone tablets called physeptone are the same drug but not prescribed for opiate addiction, are for pain... If anything he should have been prescribed that. Either way they all work the same. But it will be easier to stop when it comes to it...a small amount of 2 drugs is easier to come off than a big dose of one... Hope this helps.

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155

Re: licensetospill (# 5) Expand Referenced Message

The OP is not taking it recreationally! Herein lies the problem of why those of us who are in severe pain, and need our pain meds, cannot get them now because the insurance cos. are using the "opioid crisis" as an excuse to save money. The OP is taking the meds for CANCER, not to feel high and therefore, it is NOT a waste. Thanks to comments like yours and people like that, it is very difficult, if not impossible to get insurance to cover our meds. THANKS!

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