Can Lefra Cause An Ischemic Skin Reaction?
UpdatedMy mom is 60 year old, hypertensive, diabetic, ra on treatment. She's been on Lefra for rheumatoid arthritis for more than 10 years. She has developed subcutaneous nodules followed by ischemia of the skin above in both the thigh on lateral aspect, now spreading to posterior side and right breast. She is also experiencing severe pain that's not even controlled with oral morphine tablets. A deep biopsy of skin is showing only necrotic tissue, not other pathology. The dermatologist, rheumatologist, oncologist, physician, and plastic surgeon, are not able to daignose the condition. If anybody is aware of such a condition please reply.
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Lefra contains the active ingredient Leflunomide and it has been known to cause some bad skin reactions in some people, though it is hard to say that it is what's causing it, just from the limited information in your post.
Have any of the doctors tried having her take a break from it, to see if the condition improves, when she isn't on it?
What other medications is she taking?
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