Watson Brand Oxycodone Vs. Mallinkrodt Brand Oxycodone

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DMR76 Says:
 
I have 3 herniated disc in my lower back and severe nerve damage down my leg. I've been on Oxycodone 10/325 for the past 4 years. I have always gotten the Watson brand which would keep my pain under control somewhat up until the other day I was given Mallinkrodt brand because my pharmacy had ran out of Watson. These Oxycodone made by Mallinkrodt don't touch my pain what so ever. It's like taking a sugar pill. I'm in extreme pain and don't know what to do or how to go about this. PLEASE SOMEONE HELP

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Verwon Says:
 
Since they are both generics for Percocet, which contain Oxycodone and Acetaminophen, there is probably a slight difference in the amounts of the active ingredients that they contain, when compared to each other.

Under U.S. federal law, the FDA does allow the generics to differ from the name brand by as much as plus or minus 20% of the active ingredients. They consider this an acceptable therapeutic window and in many cases, the differences aren't significant enough to make a different and be noticeable.

However, with some generic medications, this creates a problem, because since they are only required to measure them against the name brand, this means there can be fluctuations when you switch from one generic to another.

Thus, the one you were taking that was manufactured by Watson may have contained the precise amounts of the active ingredient or, maybe even a little more, but the one that you have received from Mallinckrodt could actually contain less of them, so it may not handle your pain effectively.

And to be honest, we have had many complaints on here about the products manufactured my Mallinckrodt and their not being as effective as the same products from other brands.

The only thing I can suggest is talking to your pharmacy and asking them if they can order the ones manufactured by Watson and provide them for you, when you get your next refill.

http:/­/­www.medschat.com/­wiki/­Percocet/­

Are there any other questions?

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DMR76 Says:
 
Thanks for the info. I also forgot to mention the servere dry mouth and burning in the mouth with the Mallinckrodt. My Pharmacy recently got the Watson brand in and took care of it for me.

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Verwon Says:
 
DMR76, I actually remember experiencing the same thing, the burning in my mouth, when I used the regular Mallinckrodt Oxycodone and their Morphine tablets. If they just touched my tongue for a second, when I was taking them, the burning sensation from whatever they use in their coating was awful and took quite awhile to go away.

http:/­/­www.medschat.com/­wiki/­Morphine/­

http:/­/­www.medschat.com/­wiki/­Oxycodone/­

I am very glad your pharmacy was able to remedy the problem for you!

Are there any other questions or comments?

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the-siberian Says:
 
I have chronic pain due to multiple herniated bulging discs with pinched nerves and osteoarthritis plus chronic sciatica. I have been on endocet a 30 day supply than witched to Watson generic brand which hardly put a dent in the pain I was experiencing. The only generic brand for oxycodone was Mallinckrodt, but that's just me. They have a longer pain relieving affect. But everybody response differently to medications
Maybe my system adapts to Mallinckrodt cuz i have been on those longer than the others.

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Lisa D Says:
 
Well, they are both generic. In generic meds they main ingredient (pain killer) isn't 100%, with some. Pharmacist say they are the same but no they are not. They have to be within only 80% or more of the pain killer. Some are 85%, some more or less 80 - 100 %. Name brand is 100%. Name brand is harder to get. Your doctor has to specifically write on the script medically nec. Endocet is the highest generic I have found. The round white Watson 932 10/325 Oblong yellow pill is the best I've found, then Oblong white. I don't like the round white. Not as effective. When you fill your script specifically ask for Endocet, Oblong YELLOW. They will work better. This is only my opinion. To eaches own, but its worth a try. Good Luck!

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Lisa D Says:
 
Well, they are both generic. In generic meds they main ingredient (pain killer) isn't 100%, with some. Pharmacist say they are the same but no they are not. They have to be within only 80% or more of the pain killer. Some are 85%, some more or less 80 - 100 %. Name brand is 100%. Name brand is harder to get. Your doctor has to specifically write on the script medically nec. Endocet is the highest generic I have found. I don't like the round white. Not as effective. When you fill your script specifically ask for Endocet, Oblong YELLOW. They will work better. This is only my opinion. To eaches own, but its worth a try. Good Luck!

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Lisa D Says:
 
DISREGARD ABOVE.

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Lisa D Says:
 
I MEAN BELOW, ABOVE IS THE CORRECT REPLY

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9
Bait and Switch Says:
 
They won't have any Watson for long....probably gone now.

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Dixie Says:
 
I would like to know where I can get Watson brand for Percocet please. At a Pharmacy near I live. Escondido, Calif.

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11
Kay Says:
 
Hi~I actually called Watson & they sold out to a company called Activas. They claim they use the exact same amount of meds in this new one made by activas, however the "way they make it is different!" I have been taking the 10/325 & it has helped, but since I started taking the Activas (formerly Watson) I need 1 & 1/2 pills to help the pain, & I am going to tell my Doctor about this. I have called all over & NO ONE has the OLD Percocet by Watsons anymore. What Activas told me is that THEY WANT TO KNOW IF THIS IS NOT WORKING THE SAME, so people NEED to call them & let them know so hopefully they will go back to the way Watson made it before. Their number is #1-800=272-5525 option 2. I have never been constipated on Percocet in the 2 yrs. I have been taking it, but since I started this new Percocet I am ALOT~I am going to tell them that too. I hope this helps. There is NOTHING worse than PAIN!!!

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Fellow back pain victim Says:
via mobile
 
I don't know how you could think Watson or Endocet are even remotely better than Mallinkrodt! The first two are even physically smaller by about 30% than the Mallinkrodt brand. Watson and Endo are so week compared to Mallinkrodt that I won't even fill a scrip if the pharmacy is out of Mallinkrodt. They are the highest quality and one of the original Percocet generics. You may just need to get acclimated to them but you are slighting yourself if you stick with the Endo or Watson. They are poor quality and cheaper as a result.

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irish Says:
via mobile
 
I agree. Mallis r the way to go. Nothing touches them. Endo, watson, nothing. They r labeled m523. If u have these u r in good shape.

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14
Helen Says:
 
Has your Dr. put you on Hydroco/APAP 10-325 (Percocet) before?
This generic for Norco 10-325.
I have to take these all of the time.


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JoAnne Says:
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I have been having major issues with Mallinckrodt products. I've research this for a month now and have discovered that the 'inactive' ingredients they use in their generic brands are different from the original manufacturer AND different from other generic producers of the same products. Apparently I'm having a reaction to these. Tell your doctor this and hopefully you will get a new prescription. BE SURE you call around to different pharmacies to see which mfg they are buying from. You can google 'inactive ingredients in Oxycodone/APAP by Mallinckrodt'. The first three links should direct you to the resource that lists them. What I found interesting is that they use ingredients that are not approved by the FDA for FOOD, only drugs and cosmetics! FD&C vs D&C. Good luck!

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Brihlen Says:
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What kind if reaction did you have?

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dilaudid8 Says:
 
I really don't know what to say here I thought the brand name was better also but the gov FDA the main pain killer is oxycodone . which has to be the same its the law 2+2 is 4 its not 3 yes there is a range how much Oxycodone which can be used but all in all its the same thing. 100 percent cased close if you dont believe go to your pdr book and look up active ingredient so yes its in your head who doesn't think its the same

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Mary Says:
 
I don't agree that it is in her head! I also have severe problems and watson actually does help better than any other generic I have tried. I have also tried some generics that were like taking nothing at all. I have read allot on this subject and have found that some are not actually equal on the pain med side... Now I believe that! It is not right equal should be equal. If it is equal then why is brand so much more pain relieving when you are in the hospital? Just my opinion Good luck to all of us in real pain fighting the battle!

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daryl Says:
 
malrodt is the worst im so sorry about all u can do s crush rhem to make them a lttle stronger but im afraid your n for 30 days of no help as your doc im sure wont beleve u..they think all plls are the same...malencrodt are a placebo..mylan plls suc also// ask for endoset or qualtest ..you could print patient reviews take them an unused pills..may doc will re-rite but I doubt it.

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SweetG Says:
via mobile
 
I agree there is a big difference in Watson than any other generic oxy or hydrocodone obviously it is because you can never find Watson any more!!?? Why?? Does anyone know what pharmacys might Carry Watson or an equivalent to Watson a

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