How To Snort The New Formula Opana Er (Page 16)

Updated

I became a pain patient after I fell off a horse in March of last year and sustained spinal injuries which are still VERY painful. Opana ER was the first thing doctors gave me that helped at all and now that they have changed the formula I'm in a lot more pain. I want to break down the formula so I can insufflate it, as I am told I may get more pain relief and increase bioavailability of the drug. The new formula hardly offers the same pain relief, Please help me!

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301

Who are you talking too? You don't need to call people names. What are you 15? I am in a program a pain managment and have been for years, way before it was required. I did that so I wouldn't become an abuser I take my meds the way you are suppose to. I only have one doctor for my meds. I was in a bad accident and was in the hospital for 4 months. I almost lost my leg. It is 2 inches short than the other. I have a club foot. I am not going on even tho I have more problems than that. All I was saying people who have real chronic pain need to stick up for them self. Druggies are hurting the people with real problems. So don't speak to me that way. You get off your high horse. You are the one being awful. You are judging before you know all the facts.

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302

Happy holidays everyone, would someone tell the best way to come off Opana and what to expect. Thanks

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303

SILVER..Believe it or not, down here in South Florida, prescription fraud is huge huge and they are really cracking down on it..They have now since 2011 a new tracking system required in all major pharmacies to have this programed into their systems, it flags any prescriptions of narcotics that are filled earlier than they are suppose to be, and also flags any excessive doctors that prescribe a patient, the same patient within a certain amount of time, and JAMES, that is an educated finding and real!!! sooo because I have had the narcotic filled at different pharmicies within a proxcimity it raises a flag even without investigation, and causes the law enforcement to take it in front of legal administration and they allow a warrant to be issued to investigate the matter, this is also a nice way to get money for the judicial system, even if it isnt legit in the end, and that is the truth. My bondsman said that she has had atleast 90 cases come to her for the same reason within the last year where people are arrested off hand and totally surprised, humiliated, and are in the same standing as I was, ONE DOCTOR, SAME PRESCRIPTION EVERY MONTH, just different pharmacies filled maybe 3-5 days early and involves narcotics..They are cracking down immensily and I am fighting it 100% which I am not to worried about it, I am innocent and its just going to involve a lot of paperwork, time, and aggrevation in the end..sooo, thats the explanation of that incidence, so beware everyone and be careful, I am not sure with other states but really, Florida is a state for drug smuggling from cuba and the bahamas mostly, also illegal immigration too...;(

As for James statements, really??? Whats the reasoning behind your negative outlook on these postings and towards others?? Tis the season for others misery I guess?? .I will have to say I am sorry you are so angry and possibly unhappy, why show hatred towards others, I am glad I dont live a life like that, and I never will...It will eat away at who you are, and others sure as heck dont like to be around unhappy judgemental people, especially this time of the year...There is so much other things going on in this worldl right now, sad, scary, and questionable, the last thing we as people need rigiht now is to add to it when we come to postings like here for help and advice..So like you said, if you have nothing nice to say, then why say anything hurtful to people who are kind, and looking for help or suggestions??? You have the right to speak your mind just as anyone else does but why be inmature and call others names?..

Soo on that note, dont allow it to bother you Silver even if he was talking to you, but was probably speaking to me?. I dont let anything like that bother me and I dont feel I need to explain myself to statements like that..Why bother??? Lol HAPPY HOLIDAYS TO YOU ALL, EVEN YOU JAMES....

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304

IBI....;))

Happy Holiday's to you as well dear..Well maybe you can explain to your doctor that if your pain is subsiding and you dont feel you need pain medicine anymore, then he/she should be happy your asking for this situation and want to do it correctly. But IBI, if you are still suffering pain but you have been frightened by postings or about taking medicines every day, instead of suffering every day with pain still, maybe they can talk to you about any other alternatives to help you with your pain? I hate to hear that you are still a pain sufferer but are scared of the narcotics, I do understand this though..;)

If you wish to do this on your own though and need help, I will give you some of my advice and I am sure there are other kind people on here that may have suggestions as well. But being in the medical field for many years and experiencing this myself, I can give you some good advice ok..;))

First, how long and how many do you take a day and what the strength? I would suggest doing it slowly because its a powerful narcotic and the withdrawals would be horrible if you stopped them all at once and I am sure others would agree..Lets say if you take 30mg opana 3 x a day=90 mg a day..Try going to 2 30mg tablets a day for month or two..If your doing well with that then ask your doctor for a less mg tablet, go to 20mg..Then begin 2 x a day for a month or two..then go to another lower dose which may be 15mg or 10mg, I am not real sure on the strengths for Opana..Then at the lowest dose do 2x a day for another month or two..Then when your at the lowest dose of Opana, do one week 2 tablets a day and the next 1 tablet a day for a week or do 2 tablets one day then the next do one tablet a day..if your body is doing ok on one tablet a day for awhile then skip a day and see how you feel and you should be able to tamper down to where you are taking only a few tablets a week to down to no more tablets...This is the safest and with no withdrawals for you to do it this way dear...this way your body has tampered down slowly and you will be able to stop them..I am very proud of you wanting to get off of Opana as long as you are not in pain to where you don't feel you need a pain management for a longer time..I just don't want to see anyone in pain because they have been scared from postings or the law enforcement that has been going on with narcotics because if you are not abusing them and doing as your doctor had prescribed, then you should be just fine..As i said before though, there are many alternatives out there that can take place of pills if you don't feel you want to take them anymore and want to look for other ways to manage any pain your experiencing..

What I explained is a great way but time consuming to get off of pain pills if you wish to do most of it on your own, but also know that most doctors will help you with this process also..;)) GOOD LUCK and keep us updated on how your doing and what you have decided to do, we can be here to help you with support and to talk to..;)))

HAPPY HOLIDAY's to ALL.....

VKTORIA...;)

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305

A few groups of people are trying to stop generic Opana from being produced. They don't get it through their heads. This isn't going to stop people from abusing drugs. Druggies will find something else to abuse. God help us if it is a new street drug or they will just take a hand full of the tamper proof ones thinking it will get them their high. It won't but it could kill them or put them in the hospital or they will mix drinking with it trying to get high and that will kill them also. They just need to keep the rules in force. Keep an eye on doctors that give pain meds to patients that don't have the records to show they should have pain. People who have cancer or have had a bad accident in a car, motorcyle or war etc. They are the type patients who could be aloud to have the pain meds that help control their pain so they can live their lifes the best they can without having to stay in bed all day because they can't have the meds that help them do this because these groups are the ones that keep them in bed in pain and not able to work. We already have to sign a contract with our doctors for pain management. Go see them every month and give a urine test. Pay more and more money out every month because we with the real chronic pain are being treated like the drug abusers. Make the adults keep their meds locked up from kids. Educate kids about drug abuse. Your kids shouldn't know everything you do. They have so many rules that the doctors have to go through now, they just need to make sure the doctors do them but instead their answer is to stop medicines that help people control their pain from being produced. Stop the drug dealers. The ones who produce the drugs for the streets. The meth street labs. Instead these people are hurting the people with health problems.

Barnes supports the STOPP Act, Stop Tampering of Prescription Pills, a bill introduced in Congress this summer by Rep. Bill Keating, D- Massachusetts, and Rep. Hal Rogers, R-Kentucky. STOPP would give the FDA authority to require medications with oxycodone and hydrocodone be made tamper-resistant.

"We have the ability to prevent deaths and that's what makes this issue so compelling," Keating told CNN. "Its not a theory. It's not research. We're urging the FDA to take action and show leadership. Canada has made their decision on how to deal with it. I think if we make a decision to go with tamper-resist requirements it's going to pressure them to do the same thing."

"The impacts of these generics would not only be downright disastrous for the law enforcement and health communities, but would also jeopardize the costly, painstaking gains we're already made in our fight against this scourge -- shutting down pain clinics, sending rogue doctors to jail, and standing up interoperable state-based Rx monitoring." Rogers said in an opinion piece last month. "FDA must use its power to prevent these crushable generics from turning up in the hands of children."

Pharma recently released a statement saying they support passage of STOPP. They've called on the FDA to issue guidance to manufacturers on the use of abuse-deterrent technologies in opioids now in development or under FDA review, saying in part, "unless FDA rules on these petitions soon we believe that non-abuse-deterrent or non-tamper-resistant generic versions of those products will be able to come to market under current FDA processes for approval of generic products."

FDA spokeswoman Morgan Liscinsky told CNN she could not comment on the issue because of a pending lawsuit by Endo to block approval of the generics as well as a number of citizen petitions.

"The FDA understands how important it is to give guidance and appropriate support regarding the development of abuse-deterrent formulations of opioids and also recognizes the important role that generic drugs play in our healthcare system," Linscinsky said. "As an example of our ongoing work, the agency is currently in the process of developing a guidance on the issue of abuse deterrent formulations."

T

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I agree. Its unfortunately not going to make a difference. And soon enough, ppl will b dying bc of doing crazy things to "beat" the tamper resistance methods. I personally know ppl who will shoot morphine pills, n it is a nasty gel mixture they suck up.. ppl get "cotton fever" already n still do not stop their normal bs. (They will still reuse n do the same things that led to the abscess or problem in the first place). Millions & billions in R&D are simply doing ONE thing effectively. That is.. driving everyone's drug prices up. It is a bs tactic to give big pharmaceutical more $$$. New drug development can cost a lot, but tamper resistance is def not as costly as its made to seem. They basically do the same thing for each pill nowadays with exceptions to pills like Exalgo(Dilaudid HCl).
Anyway, give it time. Its a shame the companies talking s*** now will not hafta answer to their mistakes. But as the other poster has said, ppl will find a way to abuse these meds. Plain & simple. When these ppl start dying n getting infections bc of new untested, supposedly "inert" surfactants that were never meant to injected, we will see. It will become "acceptable deaths" bc the pharmaceutical companies wont change back after bad results. Surely not. And drugs will still be abused. Not as much at first while ppl figure it out. Then, a year down the line, ppl r od'ing like wild. Look at Fentanyl. Most ate them at first, to abuse them. Then others found ways to smoke the gel or inject it. Now they kill more ppl per yr than the first few yrs combined. Reguardless, there is nothing that can be done to deter consenting adults from doing what they want. Everyone has a vice. Cracking down on doctors wont help. "Treating" the pills to release differently will not help. There is nothing that can be done w/o changing and affecting another factor. There is NO Utopian universal answer to the problems at hand. Doctors cannot be responsible for patients that deceive them. They can only treat the problems & ensure they have all physical evidence of warranting the prescription of scheduled drugs.
The industry needs to stop passing the blame and make it clear. There is risk with medications. Maybe if they worried less about profit and more about controlling who gets prescribed them, the effective drugs could still help cancer patients and others who NEED them, while giving a different or varied formulation to the general masses.
For instance, Oxycontin should've been changed, but allowed to remain the old formula for hospital use or something. Something where its "controlled". Instead.. the pharmaceutical companies REFUSE to make a clear controlled line.. bc they rather MAKE MORE MONEY!
Its a sham. These f*cks do not care about the consumer or patient. They care about cash.
Its sad in a capitalist economy, that you can get damn near anything you want but these things that are supposedly "controlled", are the problem.. if it were truely the issue at hand, why not cut down how many are out there. Or the requirements to be given certain drugs? The control is seriously any better by simply making the meds release slower? Ppl will just take 10x as much. Great solution FDA/big pharmaceutical.

Our country is run by complete morons. And we wonder why ppl need to get fd up to cope with problems? Fix the root problem at hand to increase positively. Did ppl such as Alexander Fleming give up and simply treat one symptom at a time as they appeared? No.. he was a genius w/ OCD that took care of the root problem. The dominoes fell into place nicely after that. Instantly, WELL over 1oo% of cases of bullet wounds or near death by infection had turned around n became the basis for many many years of medical research that now allows us to make hundreds of TONS of this simple drug, wo having problems of its use. With that same kind of drive/mentality applied to our current drug problem at hand, we could've had the issue handled already.
Even in cases of hospitals also.. if one dies of an OD.. say from Heroin, it gets looked at from the pov that it is still opiates. If a person OD's from doing cocaine but had taken pills that day, the pills STILL share the blame of the death statistics. So how can it even be accurately measured on how many REAL deaths come SOLELY via the overdosing of prescription medications such as pain killers? These #'s are not accurate and imo are fudged to allow an excuse to drive up drug prices.
Btw, if one drug OD is considered death, can it be proven it is bc of "removing the tamper resistance" that the person had died? Compared to maybe they ate a lot of the tamper resistant ones? NO. The levels of a person fast releasing and a person taking a lot shows the same thing! They.. over-"dosed". Theres no medical stats saying that more ppl die one ay than the other. Do you see what I am saying ppl?

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307

There has been a bit of drama since I was last on the board. That James and Really were real jerks! Entitled to their opinions, even if they are completely ridiculous!
You all make some good points regarding the release of generic medications and the arguments of wether tamper resistant meds will make a difference!
Pharmaceutical companies only care about the almighty dollar! They make billions every year, and will protect that revenue at all costs! They have lobbyists that pour millions into congressional members "re-election campaigns" and other causes! It's really sad that congress is for sale to the highest bidder/contributor!
Anyway, I digress... I am all for generic medications to reduce healthcare costs even if it means that these can be abused. People will always find a way to abuse, no matter what they do to try and stop it!
Why should everyone be inconvenienced or worse, because of the actions of a minority of opiate pain med users?!? Ok..I'm done for now..
Hope you all have a happy holiday, and a more pain free new year! :-D

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308

Just found out that I will need back surgery again.
Not really thrilled to have to go through it again...
They want to remove 2 discs in my lumbar spine and insert artificial ones, held in place by titanium plates and screws in a new system that uses hinges to allow more flexibility. They have to cut through the stomach and the back to do this procedure! To tell you the truth I'm scared of a few things, such as never walking again, being in worst pain after, and, as strange as it may seem, waking up during the procedure, which has happened before to me! It was a horrifying event, in which I still have nightmares! The doc said that they have new equipment that prevents this, and anesthesia awareness...
Has anyone had this type of surgery? I think it is called an "A.L.I.F." or Anterior Lumbar Interbody Fusion. I would like to know the typical results and how long rehabilitation took after.
Have a nice holiday, and new year!
May you all be as pain free as possible...if I could take it away from you, I wouldn't hesitate to do so!
Sincerely, Brian

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309

One problem is Endo says they have proof that the new Opana works as well as the old but yet I read statement after statement people with bad injuries that are in chronic pain that the new don't work as well. It doesn't work as good for me either. It takes longer for it to start working and it doesn't last as long. It also upsets my intestines. I'm in more pain again. Endo is just in it for the money. If you would read everything I have read, that is what it is all about for them. They are blowing smoke in every ones eyes. Now they say the old opana isn't safe. Before they told everyone it was. That started back in 2006. They just happen to come up with a new abuse free opana just before the patent is to run out and they didn't try to stop the generic opana 7.5 and 15mg from being produced but now when it is time for Impax to release their generic opana in Jan. 2013 they are trying to stop it because of the abuse factors. Come on people wake up. We already have good rules in place. I don't like them because it makes me feel like I'm a bad person but I see why they have these rules. A signed contract with your doctor. Go to your doctor every month and take a urine test. I have been doing this for 10 years on my own. No one made me. I could have found a different doctor that I wouldn't have had to do that but I didn't. I believe that he did it for my own good so I wouldn't get in trouble with my meds. When I'm in more pain it makes it harder trying to live a normal life. I have a family to take care of. I go to work everyday because I am the only one who is working in my house. My husband has cancer and other health issues. If I don't work we lose everything and what we have isn't much but I am thankful for what we do have. I know people that have it a lot harder than I do. I am not a spring chicken anymore. I am getting close to retirement. I have gone through my saving that was for my retirement trying to take care of our bills since I am the only one working. It is very hard on me to get up every morning to go to work. I have awful nights. Most nights I only get a few hours of sleep because of the pain I am in. My friends and family think I should file for disability. They have been after me for years to do this. The way they have disability set up you can't show that you worked much. It takes 3 months to years for it to be approved. Who has the money to pay their bills? How can you go to the doctor? I could go on and on. Instead I got told to not go to work to try to get disability. I would have to lose what little I have and run up more unpaid bills. I already have high blood pressure, sure just push me over the edge. Make me have a heart attack or stroke. Make me kill myself because I can't get the help I need to control my pain so I can keep on working and take care of me and my husband and then lose everything we have. People are stating get a pain pump. That sounds good but it isn't good for everyone. Like I have told people my body rejected rods that I had in my body not just once but twice. It waited for years before my body did that. I could have died from the infection I had from it. I had to have more screws and pins put back in my body, now I am waiting for it to happen again and I'm sure it will. I have tried everything else and I even tried to take the pain and I quit taking my pain meds for over a year. It was awful. The pain was bad. It kept me from living my life. Not playing with my grandkids. I just went to work and no where else. I didn't have a life. So it is different for everyone. If you are one of those persons that the medicine is the only thing that works for you, you should be aloud to have it. Abusers will always find something to abuse.

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Ky is really pushing for generic opana not be produced. There are so many rules and systems they have put in place this past year but Endo takes all the credit for the opana not being abused because of the new abuse free ones. It isn't happening just because of this, its happening because of the new systems the doctors and pharmacies have and all the pain clinics being closed because doctors don't own them, people being made to go to pain management clinics, the drug testing, having to give your drivers licenses to be swiped into the pharmacy system every time you pick up your meds. A few years ago they started making you give your licenses every time you buy sinus medicines and your only allowed to buy one package a month because of the drug dealers making drugs. Again and again people that need certain medicines are given a hard time because of the druggies. Good people don't get heard only the bad people do. My mother told me life isn't fair. Kids should listen to their mother. So, can't these groups and the FDA see Endo is in it for the money? Abuse didn't just go down because of the new formula, there are other facts that show this.

FYI
Kentucky lawmakers took aim at prescription-abuse woes by passing legislation this year that bolstered the state's prescription monitoring system and focused on pain management clinics. The law requires all new pain management clinics to be owned by licensed medical providers and to have medical directors in charge. It also requires all doctors, dentists, optometrists, registered nurses and podiatrists who write prescriptions to use the state's prescription monitoring system, known as KASPER.

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I found this from Endo. Just last Feb. 2011 they sent or posted this. They weren't worried about opana being not safe back then. How long do you think they were working on the new abuse free opana? In Dec. 2011 it was approved and it was available March 2012 with the old formula getting ready for the patent to expire, but yet just months before that they give up 7.5 and 15mg and giving another drug company rights to make generic of those two and Endo focusing on the strengths that was most used. They state that in this letter. If all drug companies can do this when their patents are getting ready to expire they are going to do it with all drugs to make more money, not just pain medicines, it will be all meds that people most need for heart, blood pressure, anti depresses etc.

FYI
February 2011
Re:
Discontinuation
7.5 mg and 15 mg OPANA® ER (oxymorphone H Cl) Extended-Release Tablets CII

Dear Valued Customer:

Please be advised that Endo Pharmaceuticals will discontinue the sale and distribution of two
strengths of Opana® ER (oxymorphone HCl) Extended-Rellease Tablets CII. Endo estimates these
two strengths will no longer be on retail shelves on or about May 01, 2011.

63481-0522-70
5

63481-0553-70
5
Due to increased demand for Opana ER, Endo is streamlining operations to focus on the most
commonly prescribed dosages, enabling us to serve the needs of our customers while continuing to a
supply a wide range of dose strengths. Opana® ER dose strengths of 5 mg, 10 mg, 20 mg, 30 mg
and 40 mg will continue to be available at your local pharmacy. Your patients can call 1-888­
222-9845 to locate the nearest pharmacy stocking their prescribed strength of Opana ER.
Please see the enclosed full Prescribing Information including boxed warning for Opana® ER.
We thank you for your continued support of Endo Pharmaceuticals Inc. If you have any questions
please consult with your local Endo Pharmaceuticals Sales Representative or contact the Endo
Pharmaceuticals Customer Service at 1-800-462-ENDO (3 636).

Sincerely,
Product
Opana® ER (oxymorphone HCl) Extend-Release Tablets CII
15
Opana® ER (oxymorphone HCl) Extend-Release Tablets CII
Description
7.5 mg
15 mg
Packaging
100 ct. Bottles
100 ct. Bottles
A. Demir Bingol
Senior Director, Oral Pain Solutions
February 2011
Re:
Discontinuation
7.5 mg and 15 mg OPANA® ER (oxymorphone H Cl) Extended-Release Tablets CII

Dear Valued Customer:

Please be advised that Endo Pharmaceuticals will discontinue the sale and distribution of two
strengths of Opana® ER (oxymorphone HCl) Extended-Rellease Tablets CII. Endo estimates these
two strengths will no longer be on retail shelves on or about May 01, 2011.

63481-0522-70
5

63481-0553-70
5
Due to increased demand for Opana ER, Endo is streamlining operations to focus on the most
commonly prescribed dosages, enabling us to serve the needs of our customers while continuing to a
supply a wide range of dose strengths. Opana® ER dose strengths of 5 mg, 10 mg, 20 mg, 30 mg
and 40 mg will continue to be available at your local pharmacy. Your patients can call 1-888­
222-9845 to locate the nearest pharmacy stocking their prescribed strength of Opana ER.
Please see the enclosed full Prescribing Information including boxed warning for Opana® ER.

We thank you for your continued support of Endo Pharmaceuticals Inc. If you have any questions
please consult with your local Endo Pharmaceuticals Sales Representative or contact the Endo
Pharmaceuticals Customer Service at 1-800-462-ENDO (3 636).

Sincerely,

Product

Opana® ER (oxymorphone HCl) Extend-Release Tablets CII

Opana® ER (oxymorphone HCl) Extend-Release Tablets CII
Description
7.5 mg
15 mg

Packaging
100 ct. Bottles
100 ct. Bottles

A. Demir Bingol
Senior Director, Oral Pain Solutions

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312

Ms. V,

I don't approved of drug abuse, I'm just trying to prove a point here. Everyone should have a right to be able to get what helps them, a pain pump, meds or what ever helps them as long as it is legal. Endo just happens to be in the light right now because of what they are doing. Bottom line is they waited till it was time for the patent to expire so the generic opana can't be produced if that happens there won't be a generic opana until there patient expires for the new Opana in 2029. Its one of their top money making drugs. All drug companies could start doing this on all medicines.
I do hope you get all your troubles cleared up. What they have done to you isn't right. Maybe you should file a suit against them. I'm sure there is a lawyer out there that would take the case. Harassment. Merry Christmas and I hope the New Year will be better for you.

I found this from Endo. Just last Feb. 2011 they sent or posted this. They weren't worried about opana being not safe back then. How long do you think they were working on the new abuse free opana? In Dec. 2011 it was approved and it was available March 2012 with the old formula getting ready for the patent to expire, but yet just months before that they give up 7.5 and 15mg and giving another drug company rights to make generic of those two and Endo focusing on the strengths that was most used. They state that in this letter. If all drug companies can do this when their patents are getting ready to expire they are going to do it with all drugs to make more money, not just pain medicines, it will be all meds that people most need for heart, blood pressure, anti depresses etc. Medicines that you need to live and if you don't have them you could die.

FYI
February 2011
Re:
Discontinuation
7.5 mg and 15 mg OPANA® ER (oxymorphone H Cl) Extended-Release Tablets CII

Dear Valued Customer:

Please be advised that Endo Pharmaceuticals will discontinue the sale and distribution of two
strengths of Opana® ER (oxymorphone HCl) Extended-Rellease Tablets CII. Endo estimates these
two strengths will no longer be on retail shelves on or about May 01, 2011.

63481-0522-70
5

63481-0553-70
5
Due to increased demand for Opana ER, Endo is streamlining operations to focus on the most
commonly prescribed dosages, enabling us to serve the needs of our customers while continuing to a
supply a wide range of dose strengths. Opana® ER dose strengths of 5 mg, 10 mg, 20 mg, 30 mg
and 40 mg will continue to be available at your local pharmacy. Your patients can call 1-888­
222-9845 to locate the nearest pharmacy stocking their prescribed strength of Opana ER.
Please see the enclosed full Prescribing Information including boxed warning for Opana® ER.
We thank you for your continued support of Endo Pharmaceuticals Inc. If you have any questions
please consult with your local Endo Pharmaceuticals Sales Representative or contact the Endo
Pharmaceuticals Customer Service at 1-800-462-ENDO (3 636).

Sincerely,
Product
Opana® ER (oxymorphone HCl) Extend-Release Tablets CII
15
Opana® ER (oxymorphone HCl) Extend-Release Tablets CII
Description
7.5 mg
15 mg
Packaging
100 ct. Bottles
100 ct. Bottles
A. Demir Bingol
Senior Director, Oral Pain Solutions
February 2011
Re:
Discontinuation
7.5 mg and 15 mg OPANA® ER (oxymorphone H Cl) Extended-Release Tablets CII

Dear Valued Customer:

Please be advised that Endo Pharmaceuticals will discontinue the sale and distribution of two
strengths of Opana® ER (oxymorphone HCl) Extended-Rellease Tablets CII. Endo estimates these
two strengths will no longer be on retail shelves on or about May 01, 2011.

63481-0522-70
5

63481-0553-70
5
Due to increased demand for Opana ER, Endo is streamlining operations to focus on the most
commonly prescribed dosages, enabling us to serve the needs of our customers while continuing to a
supply a wide range of dose strengths. Opana® ER dose strengths of 5 mg, 10 mg, 20 mg, 30 mg
and 40 mg will continue to be available at your local pharmacy. Your patients can call 1-888­
222-9845 to locate the nearest pharmacy stocking their prescribed strength of Opana ER.
Please see the enclosed full Prescribing Information including boxed warning for Opana® ER.

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313

TO SILVER...I am sorry that you suffer so much from pain and having to be the sole provider for your home, I know that is a lot of pressure on you as a woman and also as a woman who suffers severe pain every single day...I appreciate your kind words and happy holidays, much appreciated...

I honestly dont know much about Endo or anything about pharmacetical companies, I dont read much up on them, Im very busy trying to finish my college and live my life the best I can each day, and reading bad news more than whats on the news every single day, isnt of interest to me, so much has and is going on these days, I try very hard to keep myself upbeat, confident, and not allow what may happen in the future to get me down..I do know that they will never discontinue medicines, the pharmacetical companies would go flat broke, and thats not what they want, im sure...;)

I have already talked with my husband about a suit against the city police department for what they have done to me and I am sure many others.. We will see and I will keep everyone posted too..

I wish everyone happy holidays and happiness...;)

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314

TO: CHRONIC PAIN...

Hello dear, I am sorry to hear that your going through another surgery, I know its quite a surgical procedure and the outcome will be positive, but I would suggest maybe another doctor approval just for your own mind and feel better about the surgery, maybe another suggestion on your problems may be good?? I also know its hard to have another surgeon or physician to see you without all your medical background and information...

I do know the technology and medical breakthroughs they have now are incredable, so try to be at ease about the procedure, but I know its easier said than done my friend..I know having plates put into your back is scary, but you say their putting in hinged plates which will allow more mobility and I feel you will be happy?...;)

Stay strong mentally, its amazing how positive menatlity can heal your body faster and sometimes better. The reason I am saying that is because when I worked bedsides for my patients, if they stayed strong and kept in their heads that they were gonna face whatever they were dealt, they healing was faster or if they didnt have good faith, it was much slower or even worse...Just things I have observed dear...

Keep us updated on how your doing, when the surgery is if you dont mind, so I can keep up on your recovery...;))

I wish you and your family HAPPY HOLIDAYS and if you need anything else that I can help with, advice, encouragement, or just someone to listen to, I can give you my personal email if you dont wish to express everything on here, and I will do my best to help ok..;))

Until we hear from you again, stay strong and please try to keep an upbeat attitude, you can do this...;)))

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315

Thank you Vktoria... :-) I am going to have a second opinion with a different surgeon on the 8th of Jan. Don't want to do it unless it is really necessary! I'm pretty sure it is, as my increased pain level was the reason I had the CT scan done in the first place...and I did read the report from the radiologist! It was pretty shocking to see how much worse my lumbar spine had deteriated in the last 3 years!
I just want to stop hurting so much, without taking anymore narcotics...as I take a rediculous amount as it is!!! I hope that it helps enough, that I can even reduce my dosage(getting off them alltogether would probably be wishing for too much!). Thanks for your concern... hope your holidays are filled with love & joy with your family!!!
Take care... I think this site censors email addresses' so I will leave out the symbols. xxxxxx@xxx {edited for privacy} You can figure where to put they at & period, if it is not X'd out like my full address, which I will include, but will probably be censored... xxxxxx@xxx {edited for privacy}

Editor's Note: We apologize, but aside from a few (very) rare exceptions we cannot allow personal contact information (including Facebook names) to show up in the posts. This is to protect the privacy of our visitors.

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316

TO: CHRONIC PAIN....

I am so happy your getting a second opinion my friend, I am very sorry your pain level has increased and the deteriation of your Lumbar spine my friend. i also suffer generative disk disease, sever Fibromyalgia, deteriated disk in my cervical, and I lost my right knee in an accident and also my hips have oh,,, I cannot remember what its called, but I am doing a bit better with it all as time goes by...BUT, THE PAIN PUMP REALLY REALLY HELPS ME A LOT and I am able to do more and often than before, I wish it could help everyone like it does me without surgeries to the spine, especially for you dear friend...

Well, if you can please let me know how your apppointment went, and your right the email didnt go through...I am trying to think of a way to get ahold of one another instead of here, it doesnt allow us to post personal emails?? Any suggestions?. Lol well, until we figure it out, have a MERRY CHRISTMAS, AND A HAPPY NEW YEAR....That goes for every one as well...;)))

P.s. I am very proud of you by the way, for staying so strong for yourself and your loved ones...;))

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317

You know I have a story and I hope everyone on both sides of this can understand my thought process. I was not blessed with the best health and no, I probably didn't treat my body right but I am 39 now and back on Opana. I have an addictive personality and they are cheaper on the street. I am very ADD,but that was not the only health issues I was blessed with. When I was 15 I started getting collapsed lungs, then at 18 I herniated l4-l5 and scheduled surgery. Any Dr or person who has never experienced this pain, you really have no right to say anything but it doesn't end there. Not to mention my life felt like it was being taken away, my first addiction to Lortab's began then. I had surgery a year later successfully, and I went through my first withdrawal, addiction, dependency it's all the same, I don't give a damn, I am hurting to the point my wife had to help me put on my pants. At 21 I herniated l5-s1 and was diagnosed with degenerative disk disease all while having collapsed lungs once a year or more, my second addiction / dependency to opiates, I had an experimental injection called a "Chymopapain" (spelling) injection which was painful and was not as successful as the first so it took me another year to get off the opiates.

What really sucks is that you can't be honest, you can't say yeah, I have an addictive personality but I also have the strength to gt off them because they don't believe you.

At this stage of the game, I am a 21 year old getting married and can't even get into my car without falling down, and yes there are a lot of people with much worse than I but that is not the point, we are individuals. My wife watched me flop around like a fish while watching TV and then the crawling on the floor while looking for that last lortab. I quit again but I made a clear statement to myself, if I was going to experience this much pain, then I want a controlled buzz, numb my nerves, make my life livable, the Dr prescribing the pills has no freaking idea what I am experiencing.

Yes addiction / dependency to opiates may mask the pain but I deserve the buzz if nothing else. I then got diagnosed with diabetes and a little late so I had neuropothy which is further painful at 27 I think. Well this caused me to loose too much weight and I thought I herniated another disk but the Doctors where getting scared to prescribe in fear of license and at this point they didn't see a herniated disk but I sure the hell felt one. Multiple Dr.'s didn't believe me and one decided to inject me 8 times with a steroid shot moving a half an inch up from l5-s1 to l4-l5 because he refused to give me the pills I needed, I was in tears and needless to say, for tall skinny people those shots don't work at all.

Well, I had a pain doc take me over and over prescribed anything I wanted. I am very technical so I did my best to manage and reduce the amount when I found out finally that Alieve worked better than all the pills (IN THIS CASE), so I cut myself off 80MG of methadone after 5 years. I was proud, but a year later, I was reaching down to pick up a box and I herniated l3-l4. I went to the best back surgeun and he looked at me and explained the gravity of my situation. L3-L4 was fully herniated, l4-l5 was bulging, and l5-s1 ended up being fused together.... Well, I was already buying opana off the street and you know what he gave me, a a script for 30 5MG percocet's.... WTF... His response, I know your in pain, your MRI shows it, do you have $30,00 for surgery of which he couldn't gauruntee me that my problem would go away

Now, I laughed because I couldn't afford the surgery and I sit a lot so needless to say I was in pain and the 40 MG Opana (old version) and Alieve gave me relief and the buzz that I needed to have a life and be able to concentrate. Yes I started snorting them, which was a mistake but it kept me in a state where i could work.

Yes I was sad when they changed the formula because I am in pain and I want the buzz, but now I cut them in half and it does help, doesn't give the buzz but the pain is at least bearable. Yeah I had a day or two were i felt like s*** but at least i have a sense of life and yes with a little buzz.

Now, the diabetes rotted my teeth out further making doc's think i am a crack head and that is a whole other story of pain that I am dealing with. So I end up buying my pills off the street from people who have fake MRI's and can get anything they want written for them and they don't' even have a headache.

My moral to the story - You don't have a right to judge or even comment if you haven't experienced the shooting leg pain in combination with diabetes day in ad day out. I have a very addictive personality but I still manage to keep my limit's, I never went above two pills a day and if i do, I cut it in half and half it again keeping the withdrawls from hurting....

As for the Dr.'s, I don't give a damn what you call it, addiction, dependency, or whatever, weed out t the liars and give me my damn buzz, it deadens the nerves and but don't judge me as a druggie.

As for the guys who are hitting 4 -6 40MG opana's and you aren't dying, cut it in half, it only takes a week, then do another half and get it under control.

Just my thoughts...
Thanks
A very happy but hurting person with a more drive than most.

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318

TO JON....

ON here I am trying to make it so anyone can discuss how and what they are feeling and not judge...Your judging others by your comment .....

"My moral to the story - You don't have a right to judge or even comment if you haven't experienced the shooting leg pain in combination with diabetes day in ad day out. "

We all experience pain in many ways..I have Fibromyalgia which is just as painful as neuopathy, but I am not going to tell anyone their not in pain if they arn't experiencing it...Your numbness you get from snorting will numb your pain for sure, but Im gonna tell ya, your going to fry a whole into your nasal cavaties that leads straight to your BRAIN in no time..Now, you want to talk about pain???? And once a doc sees that, you will get nothing....because they will know exactly why...

Im very sorry you have experienced the pain you have throughout your life, I truly am as I am for everyone also...Thank you for sharing your story, and I truly wish you miracles in medical breakthroughs, and if you wish to discuss with us more, I know I will listen happily....

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319

To Jon: Vktoria is right, we shouldn't judge others...but she is nicer than I am...because I think your a bit nuts!
I don't mean this in a rude and terrible way, although it will sound that way when read! I'm really not sure what your story is trying to get across to others... You seem to be more concerned with getting a "good buzz" than adequate pain relief!!! And stop using your medical and psychiatric problems as an excuse to abuse meds!
That's not living life, it's avoiding life!!! That buzz/high you seek will slowly get harder to obtain and eventually will be unobtainable... What then? Your expectations of pain management are unrealistic and unsustainable!
I truly am sorry that you have been dealt such a crappy list of medical problems...you don't deserve to have to live with the chronic pain! I think that you may need to evaluate your priorities, get a good pain doc, and enroll in therapy to find out why your using narcotics improperly. I think you still have an excellent chance of fixing things before you spiral out of control! Good luck and may god bless you! Again, I apologize for being rough, I am just concerned for your wellbeing!

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320

TO...CHRONIC PAIN...

Hi there friend, i think your a kind person, dont be hard on yourself because you say what your thinking...

how are you doing??

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