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Glyb/metform 5/500mg

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white tablet used for Type 2 dibetes


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Jim Says:
 
Active Ingredients: Glyburide + Metformin

This anti-diabetic medicine is a combination of two medicines (a sulfonylurea and a biguanide). It is used along with a diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). This medicine works by stimulating the release of your body's natural insulin and by restoring your body's proper response to insulin. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, and circulation problems, as well as sexual function problems (impotence).

SIDE EFFECTS, that may occur initially during treatment, include nausea, stomach upset, diarrhea, or weight gain. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if your stomach symptoms recur later (after you are taking the same dose for several days or weeks). A later recurrence of stomach symptoms may be due to lactic acidosis. CONTACT YOUR DOCTOR IMMEDIATELY if you experience persistent sore throat or fever, easy bleeding or bruising, severe stomach pain, yellowing eyes or skin, dark urine, unusual tiredness or weakness, unusual or sudden weight gain, mental/mood changes, swelling of the hands or feet, or seizures. THIS MEDICINE CAN CAUSE LOW BLOOD SUGAR (hypoglycemia). This effect may occur if you do not consume enough calories (from food, juices, fruit, etc). The symptoms include chills, cold sweat, blurred vision, dizziness, drowsiness, shaking, rapid heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you are in a situation where you don't have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level. TELL YOUR DOCTOR IMMEDIATELY about the reaction. To help prevent hypoglycemia, eat meals on a regular schedule and do not skip meals. Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor. If these symptoms occur, TELL YOUR DOCTOR IMMEDIATELY. Your medicine dosage may need to be increased. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

WARNING: The metformin in this combination medicine can rarely cause a condition called lactic acidosis, which can be fatal. Seek immediate medical attention if you develop any of the following symptoms of lactic acidosis: unusual tiredness (fatigue) or severe drowsiness, cold skin, muscle pain, trouble breathing or rapid breathing, or unusually slow or irregular heartbeat. Lactic acidosis is more likely to occur in patients who have certain conditions, including heart failure, kidney or livery problems, excessive alcohol use, a lack of body fluids (dehydration), x-ray or scanning procedures that require an injectable iodinated contrast drug, surgery, a serious infection, heart attack, or stroke. Also at a higher risk are those who are elderly, especially if you are over 80 years of age and have not had kidney or liver tests. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. USE OF THIS MEDICINE IS NOT RECOMMENDED if you are also taking bosentan. If you are currently using bosetan, contact your doctor before starting this medicine. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking other diabetes medicines (e.g., insulin, rosiglitazone), aspirin or aspirin-like medicines (e.g., salicylates, NSAIDs such as ibuprofen, phenylbutazone), azole antifungals (e.g., fluconazole), cimetidine, birth control pills, blood thinners (e.g., warfarin), chloramphenical, clofibrate, clomiphene, corticosteroids (e.g., prednisone), decongestants (e.g., pseudoephedrine), diazoxide, diet pills, epinephrine, estrogens, high blood pressure medicines (beta-blockers such as propranolol, calcium channel blockers such as nifedipine, ACE inhibitors such as captopril), isoniazid, monoamine oxidase inhibitors (MAOIs)(e.g., furazolindone, linezolid, moclobemide, phenelzine, procarbazine, selegiline, isocarboxazid, tranylcypromine), niacin, phenothiazines (e.g., chlorpromazine), phenytoin, probenecid, quinolone antibiotics (e.g., ciprofloxacin), rifampin, sulfonamides (e.g., sulfa antibiotics), thyroid medicine, water pills (diuretics such as hydrochlorothiazide, furosemide), fenugreek, or ginseng. DO NOT START OR STOP ANY MEDICINE without doctor or pharmacist approval. Inform your doctor of any other medical conditions including thyroid problems, blood problems (e.g., anemia, vitamin B-12 deficiency), scheduled upcoming surgery, scheduled upcoming x-ray or scanning procedures, alcohol use, certain hormonal conditions (adrenal/pituitary insufficiency, SIADH-syndrome of inappropriate secretion of antidiuretic hormone), electrolyte imbalance (hyponatremia), high blood pressure, allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have certain medical conditions including kidney disease, liver disease, congestive heart failure, metabolic conditions (e.g., diabetic ketoacidosis), recent heart attack or stroke, serious infection, or dehydration.

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