Difference In Manufacture?

Updated

I recently switched pharmacies. Previously, I was taking 5mg IR oxycodone with the boxed M on one side and the 0552 on the scored side. With the new pharmacy, I have the same prescription, only the pills have a stylized V on one side and 4810 on the scored side. For some reason, I don't seem to get the same relief with the new pills. Is this just in my head? It seems to me that 5mg of oxycodone is 5mg of oxycodone, and it doesn't much matter what the inert filler is and who packed it together. Does anyone know if there is any difference depending on the manufacturer?

8 Replies

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1

Yes, there can be a difference. The FDA does permit there to be a different between the name brand and a generic up to as much as plus or minus 20% of the active ingredient. They consider this an acceptable therapeutic window.

Since they base their manufacturing process on the name brand product and do not have to compare them to other generics, this naturally creates some differences between the amount of the active ingredient between different generic products, as well. Though some companies are much more careful about it, than others.

Some people notice no difference, but some, such as yourself, can be sensitive to any fluctuation and might find a different generic is not as effective as the one they were taking.

You can ask the pharmacy if they can get the other one ordered in for you. It is manufactured by Mallinckrodt Pharmaceuticals or you can switch back to your other pharmacy and see if they can still with that one.


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2

Hooray! I'm not crazy!

Thank you for the reply. Since posting my question, I've looked into the matter as much as I could, and all opinion seems to agree that there can be a difference. Boo la différence.

Cheers!

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3

u better believe that different manufacters are different meds. and check the price. the last prescription i had filled in tampa fl for 240 oxycodone was $1,400 yes u heard correct. highway robbery

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4

i have a round pill white on one side it has a line threw the middle on the other side it says 512 is it a percoset

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5

Yo Nick, the answer to ur question is yes. the lil white pill is a 5 mg percocet or oxycodone. I just had knee surgery and thats what dr prescribed me...

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6

is opana 40mg stronger then oxycontin 80mg or is 40mg of opana equal to 40mg of oxycontin

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7

I don't know if there is a diff and ur thoughts r logical that there should be no difference but.... I have taken both and agree that the ones with the v don't seem to work as well

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8

There are a lot of different kinds of oxy codone 30mgs...the ones with the squiggly V dark blue no one seems to like, when I go into the pharmacy the first thing I ask is what brand do you have? The Activas say A on one side and 215 on the other side, and then theres Malicinkroft which has the M on one side and the 30 (or what ever mg you are getting on the other side..I hear the A215s are stronger, but I think they are all the same and as far as the Vs nobody I know likes them

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