Axiron Side Effects

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I was prescribed Axiron for Low T and have been using it every day as prescribed for 30 days now. I have noticed some very positive side effects, such as more energy and increased sex drive. Unfortunately, however, the effects are not all positive. I've been experiencing "peaks and valleys" in the effects of Axiron. Everything I have read about this medication states that the desired results will be noticeable, and the effects will plateau (even out) in approx. 15 days. After 31 days using Axiron, I am still having severe ups and downs--most noticeably with my moods and temper. (I have increased road rage, but on the plus side, I don't cry as much during sex. Lol.) All joking aside, if anyone else has had similar experiences with Axiron treatment, I would really like to hear from you. I would also like to know the pros and cons of using Axiron vs. testosterone injection therapy.

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1

Have you discussed these issues with your doctor?

We've really only had a few people post that have used it, so far.

You can see there posts at the following links:


https:/­/­rxchat.com/­Discuss/­Axiron-deodorant-223324.htm

https:/­/­rxchat.com/­Discuss/­FOAM-APPEARS-AFTER-APPLYING-AXIRON-225796.htm

https:/­/­rxchat.com/­Discuss/­How-safe-is-Axion-Really-216689.htm


And more information on Testosterone here:

https:/­/­rxchat.com/­wiki/­Testosterone/­

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2

Thank you for the links I havew already checked these out. I have talked to my Dr. but he has never prescribed it before --- I was the first -- we live in a small town. But any info i get is great. as far as deorderant I have had to put on my med at least a half hour before applying my gel sport deorderant. that seems to work ok. i think i may look into the shots as they don't havw as many peaks and valleys -- so i hear. thank you again.
Az

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3

I have been using Axiron now for 2 months, after about 5 weeks of depo injections. I do have increased energy, and sex drive, but I also am experiencing bouts of rage. I have lost it a few times now, and even smacked my daughter in the face. (I have never lifted a finger to my kids before) I experience weird "electric shocks" some days, where it feels like someone is electrocuting me from the inside out. Also, have felt like crying for no reason at all... I had none of this with the depo, and will probably ask the dr to switch back to those injections.

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4

I took Axiron for one month and experienced several serious side effects, including:
1. Seriously swollen legs and ankles
2. Swollen hands
3. 25 pound weight gain
4. Sleeping and breathing problems when laying down to sleep.

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5

I have been taking Axiron for about 2 months now and the most significant side effect I have noticed is about a 25 to 30 pound weight gain in that brief period. My eating did not increase and my exercise routine stayed the same. What would cause this dramatic weight gain? I am thinking of discontinuing as the additional weight (increase from 230 to 260) gain may be worse than low testosterone.

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6

my prostate went from 3.6 to over 4 in a matter of a few months.

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7

I've been using Axiron for about 1 year. I have experienced swelling in my ankles/feet. My doctor is now doing a battery of test to rule out heart problems (heart failure was his first inclination when he saw the swelling). Other than that, I have enjoyed increased energy and sex drive.

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8

I have same problem. I think the axiron can be converted to estrogen(the opposite of what we want) . I have talked to a testostorone specialists in CA and he advised me of this. Said I needed estrogen blockers to go with the axiron. To talk to doc next month. I have gained 25 pounds and have none of the energy claimed.

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9

My husband has been using this medicine for a couple of months now.
I have not noticed any increase in his sex drive. However, his moods (anger) have gotten worse. He also has been more lethargic.

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10

Old post I know but I've been on 60mg of Axiron (2 pumps) for 3 weeks. I am 32 with low T, but on Axiron I feel 19 again. My temper has flared a bit more than usual. My libido is back w a vengeance (my wife can't keep up.) overall I feel amazing!!!

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11

I am finding it difficult to live with boyfriend as long as he has been using it.Iy has been over a year, and the mood swings,rage, outbursts and aggression are impossible to live with along with the denial, that this is the cause.I hate this product.I would like to hear other womens experiences dealing with this issue.am I alone?

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12

I have been on Axiron now for almost 3 months. Guess I have been lucky in that I have had none of the mood swings (no more than usual) and certainly none of the temper outbursts. My energy has been some better, but not overly noticeable. My sex drive was never an issue but I have noticed that is greater with more and better quality erections. I have been very upset with myself lately however over my increased weight gain and just assumed it was me, however from reading all these posts, it appears that it could be due to the Axiron?? Is it dangerous to just stop cold turkey?

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13

I have been on Axiron for 45 days(only 30mg a day) Blood test just showed T is lower than when I started Dr. said to double dose but I have chosen to QUIT as I have gained 15 lbs,temper flareups, glucose level up dramaticallyand breathing heavy. we are all different and I just cannot adapt to what is in Axiron.

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14

I have been taking Axiron for almost 4 months -- two pumps one for each armpit. I have not noticed much in the way of side effects. I have had a small amount of weight gain, but I don't attribute the weight gain to the Axiron, but to specific liberties I've taken with my diet. I gained about 10 pounds (210 to 220), but I'm maintaining without difficulty. There is one particular event that has me concerned, though. A couple of months ago, I had a very rapid heart rate during my sleep. I talked to my doctor about it and he did not correlate it to the Axiron. I am, however, uncertain.

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15

I was initially on Testim and immediately dropped about 30 pounds without much effort. It seemed to increase my metabolism and kill my cravings for sweets. Doctor suggested the pellets, which I did not like, and then Axerol and have now gained all the weight back. Thought it was just me, but after reading these and other posts, seems like Axerol may be the culprit. Am going to talk to my doctor about going back to Testim and keep everyone posted.

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16

I am in my 9th Month of Axiron. 45 year old with a starting TT number of 170 presently 396. I am on 1 pump a day. I do have an increase in libido,performance, energy, stamina, cognitive function. I'm back in the gym after 5 years. I have lost 25 pounds and counting. My weight loss would be higher I feel but I am putting back on a lot of muscle mass. I do have an increase in body and face acne. This is moderating over time. I do have an increase in red blood cell count but my doctor is watching it.
Yes at the beginning I did have a few rage moments. I do have a shorter temper when dealing with fools. Its like I'm 16 again but now I have the maturity to deal with it. Its like this stuff was tailor made for me.

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17

Just switched back to Testim. Will keep everyone posted.

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18

I've been using Axiron for @ 4 months now and I can truly say it works for me. I had been using Androgel 1.62% and my levels would never get over 300. I just had my first blood test, since I switched, and my level was 1350, using 4 pumps per day. Energy is amazing, erections are very good and much more easily attained (and sustained), however I have been having back acne and a little on the face, but not to bad. I haven't really had any rage problems and no weight gain at all. If anything I've lost a few pounds and am noticeably more muscular while maintaining my normal exercise routine. I also, at 42, had to start shaving daily for the first time in my life. My doctor has me down to 3 pumps now but I still feel great.

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19

Road rage or ROID rage?

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20

I'm not sure most of the replies in this thread are useful, particularly the ones detailing negative side effects, because you aren't stating what your dosage is nor telling us what your total testosterone levels are while taking this treatment.

Are you having "road rage" and aggression levels are out of control because your dosage is too high or too low and thus you're setting your testosterone levels at a less than optimal level?

If you are still feeling lethargic are you getting enough?

When you state that you are gaining weight is it due to increases in lean muscle mass, fat, or water retention? Is it healthy weight gain or is your testosterone converting to estrogen and do you need to lower your dosage or start taking aromatose inhibitors?

You people do realize that if you aren't using a correct dosage to set appropriate T levels that you probably aren't going to have the desired effect, right?

Everyone needs to give us a little more information. Most of your posts aren't very helpful.

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25

Axiron and Andro gel have been horrible for me.
53 year old and has caused unbearable hot flashes and flushing.
Swelling of legs, feet, ankles and hands.
Have gained over 25 pounds and feel horrible.
I am done.

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24

I am 60, been on Axiron on for about 4 years now, have had nothing but success with this medicine. 1 pump daily, I contribute my 50 lb weight loss to this medicine by giving me the energy to get on a treadmill every day, of course eating right helped a lot. Now the bad side, my doctor has taken me off it due to my body is now creating enough T that I need to stop for 6 months!! Been two weeks and my joints ache, and I am very lackluster. Does anyone know will this go away at some point?

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23

Ive been using Axiron for three months and had so much engery!! I felt like I was a teenager again. and then it was like over night my engery was gone!! I went back in to the doctor and had my blood work again and they said my testosterone went from 87.0 low To 540 high witch is normal and still rising!! But now even so my Testosterone is high you would think I would have all this energy like i had the first three months, But I don't Im tired all the time. Im worse now than i was before i started using it!! And they said my thyroid is normal!! Does anybody know if this is some kind of side effect? Because I've been really tired and no energy for three weeks now and I'm still using the Axiron!!

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22

Hi there I too went from 169lbs to 185lbs in less than 2 months. I gained 10lbs quickly with in the first 2 weeks. I don't know if it is muscle mass, fat, or water retention...?? I am 5 foot 9 and work in the trades so I am fairly active. My energy levels are all over the map. Some morning hi's for a few days then all of a sudden I cant stay awake in the afternoon the next week for a brief few days, then followed by dragging my ass in the morning falling asleep in my truck before work for a quick nap.

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21

Have been on Axiron for 8 weeks now. My endo put me on 60 mg or two pumps per day. My starting testosterone level was 179. I have not re-checked it yet, but I am able to work out regurarly and recover quickly. I am 52 years old and I finally feel like I did when I was younger. Sex life has improved, but not as much as hoped. However, I can honestly say that It has changed my life profoundly, for the better. No acne, no weight gain, no adverse side effects. Just a regular exercise routine and fantastic results. Thank you Axiron, I am truly greatful for your existence!!

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